The literature cases are almost all from case reports, which are highly biased towards P/LP variants in rare genes, likely monogenic (disease causal), in cases that are somehow remarkable (e.g., severe CVS phenotype, syndromic), and ascertained from the wider population
Strategies for managing this period include maintaining close communication with your healthcare provider about side effects, using all available anti-nausea strategies proactively rather than reactively, accepting that some temporary discomfort accompanies effective treatment, focusing on the progress already made rather than the challenges remaining, and remembering that 85% of patients report minimal side effects by month four
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Symptoms range from moderate to severe anemia
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